The impact of continuous renal replacement therapy on antibiotic pharmacokinetics in critically ill patients
… infections in critically ill patients undergoing continuous … /or sepsis [Citation9], a life threatening
organ dysfunction caused by a … 30 critically ill patients on meropenem, higher or extended …
organ dysfunction caused by a … 30 critically ill patients on meropenem, higher or extended …
[HTML][HTML] Population pharmacokinetics of standard-dose meropenem in critically ill patients on continuous renal replacement therapy: a prospective observational trial
D Onichimowski, A Będźkowska, H Ziółkowski… - Pharmacological …, 2020 - Springer
… for potential effects on antibiotic dosing in critically ill patients … used to treat life-threatening
infections in the ICU. According … , as long as you give appropriate credit to the original author(s…
infections in the ICU. According … , as long as you give appropriate credit to the original author(s…
[HTML][HTML] Drug dosing considerations in critically ill patients receiving continuous renal replacement therapy
SM Jang, S Infante, A Abdi Pour - Pharmacy, 2020 - mdpi.com
… injury (AKI) due to life-threatening fluid overload and/or … , meropenem’s CL NR for patients
with normal renal function (… serious infections in critically ill patients. Due to decreased …
with normal renal function (… serious infections in critically ill patients. Due to decreased …
Practical considerations for individualizing drug dosing in critically ill adults receiving renal replacement therapy
S Kanji, C Roger, FS Taccone… - … and Drug Therapy, 2023 - Wiley Online Library
… and one on meropenem, suggest that increased dosing for … In critically ill patients with
life-threatening bacterial infections, the … use are early and appropriate empiric therapy.(17) …
life-threatening bacterial infections, the … use are early and appropriate empiric therapy.(17) …
Meropenem pharmacokinetics in critically ill patients with or without burn treated with or without continuous veno‐venous haemofiltration
… are at high risk for developing life-threatening infections, … elucidate the effects of burn and
CVVH on meropenem PK using … current clinical dosing regimens to achieve appropriate PK/PD …
CVVH on meropenem PK using … current clinical dosing regimens to achieve appropriate PK/PD …
Recommended antibiotic dosage regimens in critically ill patients with augmented renal clearance: a systematic review
CM Silva, JP Baptista, I Santos, P Martins - International Journal of …, 2022 - Elsevier
… In addition, critically ill patients show a higher risk of infection … and enabling appropriate
attainment of PK/PD targets. … , one of eight studies with meropenem and in the only study with …
attainment of PK/PD targets. … , one of eight studies with meropenem and in the only study with …
Meropenem target attainment and population pharmacokinetics in critically ill septic patients with preserved or increased renal function
M Gijsen, O Elkayal, P Annaert… - Infection and Drug …, 2022 - Taylor & Francis
… insight into meropenem PK in critically ill patients with … antibiotic used to treat life-threatening
infections in the ICU. It is … The effect of increased meropenem CL on the late sampling day …
infections in the ICU. It is … The effect of increased meropenem CL on the late sampling day …
… evaluation of pharmacokinetic models for model-informed precision dosing of meropenem in critically ill patients undergoing continuous renal replacement therapy
LM Schatz, A Brinkmann, A Röhr, O Frey… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
… meropenem in critically ill patients receiving continuous renal replacement therapy (CRRT)
might impact … , altered renal clearance) (3). In addition, the use of supportive extracorporeal …
might impact … , altered renal clearance) (3). In addition, the use of supportive extracorporeal …
[HTML][HTML] The effect of a loading dose of meropenem on outcomes of patients with sepsis treated by continuous renal replacement: study protocol for a randomized …
SQ Ni, WB Teng, YH Fu, W Su, Z Yang, J Cai, JN Xu… - Trials, 2022 - Springer
… detected at the infection site during meropenem treatment, the … The appropriate alpha value
of primary outcomes in each … can be delayed as critically ill patients are often incapacitated. …
of primary outcomes in each … can be delayed as critically ill patients are often incapacitated. …
[HTML][HTML] … of meropenem in patients with sepsis and acute kidney injury before and after initiation of continuous renal replacement therapy: a prospective observational …
I Nowak-Kozka, KJ Polok, J Górka, J Fronczek… - Pharmacological …, 2020 - Springer
… Acute kidney injury (AKI) is a common life-threatening … used in the management of critically
ill patients with AKI [13]. … concentrations in urine, ultrafiltrate, and at the site of infection. The …
ill patients with AKI [13]. … concentrations in urine, ultrafiltrate, and at the site of infection. The …